CLINICAL TRIAL REPORTS

Read a clinical trial report section by section, with the source a click away

A clinical trial report is long and tightly structured: who was enrolled, how they were randomized, what was measured, what happened and what harms were recorded, often with key details in tables or appendices. Put the report PDF in a Search+ workspace, ask about each part in plain language, and open the cited passage to read exactly what the investigators reported.

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Last updated October 2026

How to read a trial report with Search+

  1. Upload the report and the protocol if you have it

    Add the trial report or journal article. If the protocol, statistical analysis plan or supplementary appendix is available, add it too, whether it is a PDF or a Word document, since many design details are only there.

  2. State what you are checking

    Use Workspace Context for your purpose, for example "I am checking whether the reported primary outcome matches the protocol; quote numbers exactly as written". Search+ applies it to each question.

  3. Ask part by part

    Ask about the population, then the intervention and comparator, then the outcomes and harms. Open each citation to see the sentence or table text the answer came from.

Questions readers ask about a trial report

Population

Who was eligible, how many were randomized, and how many completed the trial?

Comparator

What did the control group receive, placebo or an existing treatment, and at what dose?

Primary outcome

What was the primary endpoint, when was it measured, and what result does the report give for it?

Harms

Which adverse events were reported more often in the treatment arm, and how were serious events defined?

Dropouts

How many participants withdrew from each arm, and what reasons does the report give?

Registration

Does the report give a trial registration number, and does it mention changes to the protocol?

What reading a clinical trial report needs

A standard structure helps you navigate

Reports of randomized trials commonly follow reporting guidance such as CONSORT, with set places for the participant flow, the outcomes and the harms. Ask for the participant flow first; it tells you who the results describe.

Protocol and report can differ

Outcomes, analyses or sample sizes are sometimes changed after a trial starts. Comparing the report with the registered protocol is how readers spot this, so ask about each and compare the cited passages.

Relative and absolute effects tell different stories

A result can be reported as a relative change, an absolute difference or both. Ask for every form the report gives, and read them in the cited text.

Tables and appendices hold the detail

Baseline characteristics, harms by arm and subgroup results are often in tables or appendices. Ask for the figure you need, then check it against the table in the report, because AI answers can misread dense tables.

Answers tied to the report

Each answer cites the supporting excerpt, with a page or section reference when the report provides one, and Search+ does not invent locations the document does not contain.

Older reports and scans

Search+ reads scanned reports with OCR, which helps with older trials archived as page images. Faint or skewed scans can garble a number, so verify figures in the cited excerpt against the original.

Sections of a trial report and what to ask

SectionWhat it usually coversA question to ask Search+
Background and objectivesWhy the trial was run and its hypothesisWhat question was this trial designed to answer?
Methods: designRandomization, blinding, arms, settingHow were participants allocated, and who was blinded?
Methods: participantsEligibility criteria and recruitmentWhat were the main exclusion criteria?
Methods: outcomesPrimary and secondary endpoints, timingWhich outcome was primary, and when was it assessed?
Results: participant flowScreened, randomized, analyzed, lostHow many participants were analyzed in each arm?
Results: outcomesEffect estimates and their precisionWhat does the report give for the primary endpoint?
HarmsAdverse events by arm and severityHow many serious adverse events occurred in each arm?
Discussion and limitationsInterpretation and weaknessesWhat limitations do the authors acknowledge?

What is a clinical trial report?

A clinical trial report is a document that describes how a clinical study of an intervention was designed and run and what it found, including the participants, the outcomes measured, the results and the adverse events. It may be a journal article, a registry results summary or a full clinical study report.

A trial protocol is the plan written before the trial runs; the report describes what was actually done and found. Search+ can read both, and it answers from the text without judging the trial's quality or giving medical advice.

Clinical trial report questions

Can Search+ summarize a clinical trial report?
Yes. Ask for a summary and the answer cites the passages it used. For a careful read, ask about design, participants, outcomes and harms separately so each has its own citations.
Can it find the numbers for the primary outcome?
Ask for the primary endpoint result and Search+ answers from the report with a citation. Read the cited text or table, because exact figures are easy to misread out of context.
Can it compare the report with the trial protocol?
Put both documents in one workspace and ask whether the outcomes and analyses match. The answer cites each document so you can compare the wording yourself.
Does it tell me whether a treatment works for me?
No. Search+ helps you read what the trial report says. It does not give medical advice; talk to a qualified clinician about any treatment decision.
What if the report is a scanned copy?
Upload it as it is: Search+ reads scanned reports with OCR. Tables in a scan are the weak spot, so before you rely on an event count or a percentage, open the citation and compare it with the scanned page.
Can an answer miss something in the report?
Yes. AI answers can be incomplete or inaccurate, so open the citation and check the report before relying on any figure.

Read what the trial actually reported

Start a workspace, upload the report and its protocol, and ask about each section in turn.

Start a workspace